anal fistula and hemorrhoid
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Aged from 18 to 65 years old, with no restriction on gender; 2.Meeting the diagnostic criteria for anal fistula or hemorrhoid; 3.Scheduled to receive surgical treatment at the collaborative center; 4.Voluntarily participating in this study and signing the informed consent form; 5. Being able to cooperate with sample collection and relevant follow-up procedures.
Exclusion criteria
Exclusion criteria: 1. Combined with intestinal diseases such as inflammatory bowel disease, intestinal tumors, chronic diarrhea and constipation; 2. Patients complicated with underlying endocrine diseases including diabetes and hyperthyroidism; 3.Patients complicated with skin diseases such as psoriasis and vitiligo; 4.Those with immunodeficiency diseases (e.g. HIV infection), autoimmune diseases (e.g. rheumatoid arthritis), or long-term use of immunosuppressants; 5.Received probiotic preparation treatment within 3 months before admission; 6.Pregnant or lactating women; 7.Combined with severe systemic diseases such as hepatorenal insufficiency, cardiovascular diseases and coagulation disorders; 8.With a history of intestinal surgery or perianal trauma within the recent 3 months (excluding anal fistula-related conditions); 9.Those with contraindications or allergies to study-related procedures; 10.Subjects deemed unsuitable for participation in this clinical trial by the researchers.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| microbial species;Densities of different microbial species; | — |
Countries
China
Contacts
Shanghai Changhai Hospital