Patients whose dialysis catheter was not removed after CRRT treatment
Conditions
Interventions
Experimental group:After CRRT, use 4% sodium citrate to lock the catheter, once every 24 hours, until the catheter is removed.
Control group:After CRRT, lock the catheter with 1250 U/ml heparin sodium, once every 24 hours, until the catheter is removed.
Sponsors
Chengdu University of Traditional Chinese Medicine Affiliated Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Age =18 years, regardless of gender; 2. Patients in the ICU who have undergone CRRT and have not had the dialysis catheter removed; 3.Use of a temporary central venous dialysis catheter as the vascular access; 4.Expected catheter retention =48 hours; 5.Signed informed consent.
Exclusion criteria
Exclusion criteria: 1.Known allergy to heparin or sodium citrate; 2. Existing catheter dysfunction or infection before enrollment; 3. Absolute contraindications to the use of heparin or citrate; 4. Pregnant or breastfeeding women; 5. Participation in other interventional studies; 6. Considered unsuitable for participation in this study by the investigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of catheter dysfunction; | — |
Secondary
| Measure | Time frame |
|---|---|
| Catheter retention time;Catheter-related bloodstream infection;Catheter-related thrombosis;Catheter-related infection;Bleeding at puncture site;Platelet variation value;Changes in coagulation indicators;ICU hospitalization duration;Reason for catheter removal;ICU all-cause mortality; | — |
Countries
China
Contacts
Public ContactJiang Dawei
Chengdu University of Traditional Chinese Medicine Affiliated Hospital
Outcome results
None listed