Radiation vaginitis
Conditions
Interventions
Observation Group:In addition to the routine care for radiotherapy of cervical cancer, triethanolamine cream (Biafin) is also used.
Control group:Conventional flushing
Sponsors
Fujian Cancer Hospital
Eligibility
Sex/Gender
Female
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Age: 18-75 years old; 2. Those diagnosed with cervical cancer by histological pathology and receiving radiotherapy with a total radiation dose of >=70Gy; 3. ECOG score of 0-2 (Annex 3); 4. Normal mental state and clear consciousness; 5. Be able to cooperate with the visitor; 6. Sign the informed consent form.
Exclusion criteria
Exclusion criteria: Any patient who meets any of the following criteria cannot be enrolled: 1. Those with severe immune deficiency (such as those who have recently received bone marrow transplantation, with long-term high-dose glucocorticoids > 20 mg/ day for more than 2 weeks); 2. Congenital vaginal malformations; 3. Patients who are pregnant, breastfeeding, or have plans and the possibility of becoming pregnant; 4. Other conditions that the researcher deems unsuitable for enrollment (such as: previous allergy history to triethanolamine cream, etc.).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence and severity of radiation vaginitis; | — |
Secondary
| Measure | Time frame |
|---|---|
| Vaginal mucosal healing rate;EORTC Quality of life Questionnaire (QLQ-C30+QLQ-CX24);Visual Analogue Scale;Effective vaginal length;Bacterial flora detection; | — |
Countries
China
Contacts
Public ContactQin Xu
Fujian Cancer Hospital
Outcome results
None listed