Study on the Effects of Transcranial Direct Current Stimulation Combined with Neuromuscular Electrical Stimulation on Postural Control in Individuals with Chronic Ankle Instability

The Effects of Transcranial Direct Current Stimulation Combined with Neuromuscular Electrical Stimulation on Postural Control in Individuals with Chronic Ankle Instability

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2600125908

Enrollment

Unknown

Registered

2026-06-01

Start date

2026-06-01

Completion date

Unknown

Last updated

2026-06-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic ankle instability (CAI)

Interventions

NMES intervention group:neuromuscular electrical stimulation

tDCS intervention group:Contraindications to transcranial direct current stimulation

Combined intervention group:Contraindications to transcranial direct current stimulation (tDCS) and neuromuscular electrical stimulation (NMES)

Control Group:Sham stimulation

Eligibility

Sex/Gender

All

Age

18 Years to 35 Years

Inclusion criteria

Inclusion criteria: 1.Aged 18–35 years, male or female; 2.History of at least one significant unilateral ankle sprain (at least 12 months ago), accompanied by pain and swelling, and resulting in at least one day of interrupted normal physical activity; 3.Subjective feeling of instability or repeated "giving way", with a Cumberland Ankle Instability Tool (CAIT) score <=24; 4.Fully understand the purpose of the study and all testing procedures, and voluntarily participate with signed informed consent;

Exclusion criteria

Exclusion criteria: 1.Acute musculoskeletal injury of the lower limb (other than chronic ankle instability) within the past 3 months; 2.Presence of vestibular dysfunction, visual impairment, or neurological disorders (e.g., history of epilepsy) that affect balance and postural control; 3.History of lower limb or spinal surgery, or obvious lower limb joint deformity; 4.Contraindications to transcranial direct current stimulation (tDCS) or neuromuscular electrical stimulation (NMES), such as presence of metal implants (especially in the head or a pacemaker), skin lesions, or extreme sensitivity to electrical current; 5.Currently receiving other specialized rehabilitation training for the ankle;

Design outcomes

Primary

Measure	Time frame
dynamic balance performance;static balance performance;	—

Secondary

Measure	Time frame
CAIT score;Foot and Ankle Ability Measure,FAAM;Neuromuscular control indicators;	—

Countries

China

Contacts

Public ContactKun Wang

Kunshan Rehabilitation Hospital

wangkun-mtt@163.com+86 512 50760352

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Jun 11, 2026