Postoperative Delirium in Elderly Patients:Postoperative delirium in elderly patients is a common acute brain dysfunction syndrome following surgery. It is characterized by an acute and transient alteration in cognitive function occurring within the first week after surgery (particularly within 24 to 72 hours). Its core features include:1.Acute Onset: Symptoms appear suddenly.2.Fluctuating Course:
Conditions
Interventions
Routine Clinical Monitoring Group:Anesthetic dosages were adjusted by experienced anesthesiologists based on traditional parameters such as heart rate, blood pressure, and oxygen satur
Depth of Anesthesia Monitoring Group:Anesthetic dosage was adjusted based on vital signs and the Ai parameter monitored in real-time by the ConView system to maintain stable anesthesia de
Sponsors
The Second Affiliated Hospital of Inner Mongolia University
Eligibility
Sex/Gender
All
Age
65 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1.Aged between 65 and 80 years; 2.Scheduled for elective surgery (with an estimated duration of 1 to 3 hours); 3.American Society of Anesthesiologists (ASA) physical status I–II; 4.Informed consent obtained and signed by family members; 5.Preoperative fasting for more than 8 hours, with no administration of premedication (e.g., sedatives, analgesics, etc.).
Exclusion criteria
Exclusion criteria: 1.Concomitant neurological diseases (e.g., epilepsy, cerebral palsy, cognitive impairment, etc.); 2.Severe insufficiency of cardiac, pulmonary, hepatic, or renal function; 3.Uncorrected electrolyte disturbances or acid-base imbalance; 4.Allergy to anesthetic agents used in this study; 5.Poor skin condition precluding the application of EEG electrodes; 6.High surgical urgency requiring rapid sequence induction of anesthesia; 7.Inability of the patient and family to cooperate with postoperative assessments; 8.Participation in other clinical drug trials within the past 3 months; 9.Patients deemed unsuitable for participation in this trial by the investigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Early postoperative recovery indicators;Electroencephalographic parameters;Incidence and severity of postoperative delirium; | — |
Countries
China
Contacts
Public ContactWang Xiao Dong
The Second Affiliated Hospital of Inner Mongolia University
Outcome results
None listed