gestational diabetes
Conditions
Interventions
Double negative control group:none
Simply overweight/obese group:none
GDM group alone:none
Double exposure group:none
Sponsors
Shengjing Hospital Affiliated to China Medical University
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1. Ultrasound measurements of various fetal growth indicators were consistent with gestational age, with no known recognizable genetic or chromosomal abnormalities; 2. All participants underwent an oral glucose tolerance test (OGTT) screening for gestational diabetes mellitus (GDM). The diagnostic criteria were based on the revised Chinese standards of August 2014. GDM was diagnosed if the OGTT results conducted between 24 and 28 weeks of gestation met any one or more of the following criteria: (1) Fasting blood glucose >= 5.1 mmol/L, (2) 1-hour blood glucose >= 10.0 mmol/L, (3) 2-hour blood glucose >= 8.5 mmol/L. For confirmed GDM cases, good blood glucose control was defined as HbA1c < 6.0%; 3. Gestational age of 26–30 weeks; 4. All enrolled cases had clear images, with the target positioned at the center of the image, a clean and unobstructed background, clearly showing the fetal four-chamber heart view.
Exclusion criteria
Exclusion criteria: 1. Multiple pregnancy; 2. Maternal history of smoking, drinking, hypertension, pregestational diabetes (PGDM), heart and liver disease, combined with preeclampsia, thyroid dysfunction, autoimmune diseases and other chronic diseases; 3. Fetal heart structure abnormalities (such as congenital heart disease, etc.), arrhythmias or chromosomal abnormalities. 4. Fetal growth restriction (FGR) or macrosomia.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| global sphericity index;left ventricular ejection fraction;left ventricular septal wall strain;left ventricular global longitudinal strain; | — |
Countries
China
Contacts
Public ContactYu Wang
Shengjing Hospital Affiliated to China Medical University
Outcome results
None listed