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Efficacy and safety of glycerin enema in bowel preparation for colonoscopy in patients with acute lower gastrointestinal bleeding: a multicenter, randomized, controlled trial

Efficacy and safety of glycerin enema in bowel preparation for colonoscopy in patients with acute lower gastrointestinal bleeding: a multicenter, randomized, controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600125859
Enrollment
Unknown
Registered
2026-06-01
Start date
2026-06-01
Completion date
Unknown
Last updated
2026-06-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lower gastrointestinal bleeding

Interventions

Group A:Bowel preparation was performed using the standard protocol of oral PEG electrolyte solution. The specific method is as follows : the subjects were instructed to take 4LPEG electrolyte solutio
Group B:Glycerin enema was used for bowel preparation. The specific method is : ask the subject to insert the anus in the lateral position ( 6-10 cm ). The liquid was slowly injected into the rectum.

Sponsors

Seventh Medical Center, General Hospital of Chinese PLA
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 85 Years

Inclusion criteria

Inclusion criteria: 1. Age 18-85 years ; 2.Among patients with acute lower gastrointestinal bleeding, patients with endoscopic intervention factors or suspected left hemicolon bleeding, such as colon polyps after endoscopic resection, bloody or mucous bloody stools, positive digital rectal examination, etc. ; 3.Patients volunteered to participate in this study, I and my family informed consent and signed informed consent.

Exclusion criteria

Exclusion criteria: 1.Hemodynamic instability or hemoglobin concentration < 70g / L ; 2.Patients after colorectal resection ; 3.Patients with known or suspected gastric obstruction or perforation ; 4.Known hemorrhoids patients with bleeding ; 5.Patients with suspected UGIB or small intestinal bleeding combined with medical history or upper gastrointestinal endoscopy, nasogastric tube aspiration ; 6.Important functional organ failure such as heart failure ( NYHA III or IV ), severe liver and kidney failure ; 7.Patients with Oakland score <= 8 and bleeding has been self-limiting stop ; 8.suspected or confirmed pregnancy.

Design outcomes

Primary

MeasureTime frame
BBPS score of left colon under endoscopy;

Secondary

MeasureTime frame
Completion rate of bowel preparation;Bowel preparation recovery rate;BBPS score under total colonoscopy;Diagnosis rate of bleeding lesions;Operating time;Repeated inspection rate;Patients ' overall acceptance of the preparation plan;

Countries

China

Contacts

Public ContactJin Peng

Seventh Medical Center, General Hospital of Chinese PLA

jinpeng@301hospital.com.cn+86 134 6667 1195

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Jun 11, 2026