Intraoperative hypotension (IOH): From the start of anesthesia to the end of anesthesia, SBP <90 mmHg or MAP <65 mmHg measured by any method, lasting for at least 1 minute.
Conditions
Interventions
Sponsors
Peking Union Medical College Hospital
Eligibility
Sex/Gender
All
Age
65 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.PUMCH retrospective cohort from January 1, 2015 to December 31, 2025; PUMCH prospective cohort starting from March 1, 2026. 2.Elective surgery. 3.General anesthesia. 4.Age >= 65 years. 5.Signed informed consent for the study, applicable to the prospective cohort.
Exclusion criteria
Exclusion criteria: 1.Absence of non-contrast abdominal CT within 6 months before surgery, or CT images of poor quality or unavailable for analysis. 2.Cardiac surgery, ascending aortic or aortic arch surgery, pheochromocytoma or paraganglioma surgery, and gastrointestinal endoscopy procedures. 3.Extreme BMI values, defined as BMI 70 kg/m^². 4.Missing intraoperative vital-sign monitoring data. 5.Missing key clinical baseline characteristics. 6.Failure to undergo the metabolism-related laboratory tests required for the study and prescribed by the investigators for any reason, applicable to the prospective cohort. 7.Failure to undergo the body measurements required for the study for any reason, applicable to the prospective cohort. 8.Loss to follow-up, applicable to the prospective cohort.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Intraoperative hypotension (IOH); | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative Clavien-Dindo classification of postoperative complications;Postoperative WHODAS 2.0 12-item version score;Postoperative all-cause mortality; | — |
Countries
China
Contacts
Public ContactLe Shen
Peking Union Medical College Hospital
Outcome results
None listed