Degenerative Cervical Myelopathy (DCM)
Conditions
Interventions
Sponsors
Beijing Jishuitan Hospital, Capital Medical University
Eligibility
Sex/Gender
All
Age
40 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1.Healthy control group: (1) No symptoms or signs of spinal cord dysfunction; (2) No history of spinal cord injury or surgery; (3) Cervical MRI scan without spinal cord compression deformation; 2.DCM Postoperative patient group: A patient who underwent a posterior cervical laminoplasty at the Spinal Surgery Department of Beijing Jishuitan Hospital due to DCM, two years postoperatively; 3.DCM Preoperative patient group: (1) Patients with degenerative cervical spinal stenosis, cervical disc herniation, or ossification of the posterior longitudinal ligament in cervical degenerative diseases; (2) The symptomatic diagnosis is spinal cord type, and the nerve localization is consistent with imaging; (3) For patients who have failed formal conservative treatment and plan to undergo anterior or posterior cervical surgery; (4) No clear surgical contraindications; (5) Patient informed and agreed to enter this study; 4.Three groups common criteria: age between 40 and 70 years;
Exclusion criteria
Exclusion criteria: 1.Healthy control group: (1) Symptoms or signs of spinal cord dysfunction; (2) History of spinal cord injury or surgery; (3) Cervical MRI scan shows compression and deformation of the spinal cord; 2.DCM Postoperative patient group: (1) Acute exacerbation of spinal cord dysfunction after trauma; (2) Combined brain, thoracolumbar, or peripheral neuropathy; (3) Suspected nerve damage or C5 nerve root paralysis related to surgery; (4) Due to reasons such as metal plants and claustrophobia, 7T MRI scans cannot be performed. 3.DCM Preoperative patient group: (1) Patients with cervical traumatic fractures and dislocations or aggravated spinal cord dysfunction after trauma; (2) Cervical infectious lesions; (3) Cervical spine tumors; (4) Uncontrollable active infections exist throughout the body; (5) Surgical treatment is not allowed for other illnesses in the body; (6) Lack of autonomous behavioral ability; (7) Patients with nerve root type or mixed type, combined with severe thoracic and lumbar nerve compression or other brain, spinal cord, peripheral nerve lesions that may interfere with clinical evaluation; (8) Patients with a history of cervical spine surgery that interferes with clinical evaluation;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 7 Tesla magnetic resonance imaging;abbreviated as JOA score; | — |
Secondary
| Measure | Time frame |
|---|---|
| 10-Second Finger Clench-Extension Test;Triangle step test, 10-second step-in-place test;Subjective symptoms or objective signs of spinal cord dysfunction; | — |
Countries
China
Contacts
Public ContactXiao Han
Beijing Jishuitan Hospital, Capital Medical University
Outcome results
None listed