Gout
Conditions
Interventions
Healthy Control group:NA
Gout Group:NA
Sponsors
First Affiliated Hospital of Kunming Medical University
Eligibility
Sex/Gender
Male
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. All patients meet the 2015 ACR/EULAR Gout Classification Criteria. 2. Age 18-60 years. 3. Right-handed. 4. Willing to participate in the study and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Presence of systemic lupus erythematosus, rheumatoid arthritis, ankylosing spondylitis, Sjogren's syndrome, or other connective tissue diseases classified by standard criteria. 2. Patients with organic brain disease or neurological disorders (e.g., history of traumatic brain injury, surgery, Parkinson's disease, or epilepsy) that may interfere with brain imaging. 3. Patients with severe active psychiatric symptoms (e.g., severe behavioral disorders and consciousness disorders). 4. History of alcoholism or drug abuse. 5. Contraindications to MRI examination (e.g., claustrophobia, metal implants, etc.). 6. Severe clinical conditions that may lead to brain atrophy (e.g., history of hypertension, diabetes, stroke, renal insufficiency, etc.). 7. Abnormal brain structure indicated by routine MRI plain scan.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Gray matter volume (GMV), white matter integrity, and functional connectivity strength;Significant risk SNPs screened in GWAS analysis of gout patients in Yunnan.?; | — |
Countries
China
Contacts
Public ContactLiu Shuang
First Affiliated Hospital of Kunming Medical University
Outcome results
None listed