glioma
Conditions
Interventions
Observation group:None
Sponsors
The Second Affiliated Hospital, Air Force Medical University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.Participants aged >=18 years 2.Karnofsky Performance Status (KPS) score >=60 3.Newly diagnosed patients with histopathologically confirmed high-grade glioma (WHO grade 3–4) 4.Capable of basic comprehension and self-assessment 5.Voluntarily provided written informed consent 6.Scheduled to receive conventionally fractionated radiotherapy 7.Estimated life expectancy >=6 months
Exclusion criteria
Exclusion criteria: 1.Prior history of cranial radiotherapy 2.Concurrent other active malignancies 3.Severe cognitive impairment or psychiatric disorders 4.History of severe organic or functional organ diseases 5.Neurological conditions that may interfere with fatigue assessment 6.Pregnant or lactating women
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Severity of Cancer-related Fatigue (CRF) — continuous variable;Rate of Moderate-to-Severe Cancer-related Fatigue (binary outcome); | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence and Severity of Sleep Disturbance/Disorder;Incidence and Severity of Anxiety and Depression; | — |
Countries
China
Contacts
Public ContactHe Dongjie
The Second Affiliated Hospital, Air Force Medical University
Outcome results
None listed