Motor Memory Consolidation Deficits
Conditions
Interventions
M1-cTBS group:Healthy subjects were randomly assigned to the M1-cTBS protocol. The coil was placed over the left M1 area, tangential to the scalp, with the handle pointing backward, at a 45-degree ang
stimulation intensity: 80% of the resting motor threshold.
M1-sham group:Healthy subjects were randomly assigned to the M1-sham protocol. During the sham stimulation, the coil was placed at a 90-degree angle to the scalp. The cTBS protocol was as follows: thr
Sponsors
Guangdong Provincial People’s Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 30 Years
Inclusion criteria
Inclusion criteria: 1. Aged between 18-30 years, regardless of gender; 2. Assessed as right-handed on the Edinburgh Handedness Inventory; 3. Have no knowledge of motor sequence learning tasks; 4. Clearly understand the purpose and procedures of this study, agree to cooperate with evaluation, treatment, and follow-up, and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. History of neurological disorders; 2. History of psychiatric disorders; 3. History of alcohol and drug abuse; 4. History of epileptic seizures; 5. Metal implants in the head, neck, or chest; 6. Other contraindications for TMS assessment and treatment; 7. Training as a professional typist or professional musician; 8. Diseases affecting task performance (such as rheumatoid arthritis).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sequential reaction time task response time; | — |
Secondary
| Measure | Time frame |
|---|---|
| Accuracy of the serial reaction time task;TMS evoked potential;Functional connection; | — |
Countries
China
Contacts
Public ContactXu Guangqing
Guangdong Provincial People’s Hospital
Outcome results
None listed