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Study on LDH/albumin ratio and renal interstitial fibrosis in IgAN

Independent association of lactate dehydrogenase-to-albumin ratio with moderate-to-severe tubulointerstitial fibrosis in IgA nephropathy

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600125840
Enrollment
Unknown
Registered
2026-06-01
Start date
2026-06-01
Completion date
Unknown
Last updated
2026-06-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

IgA nephropathy

Interventions

T0 group:none
T1+T2 group:none

Sponsors

Fuzhou University Affiliated Provincial Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Age >= 18 years; 2. Pathologically confirmed primary IgA nephropathy by renal biopsy; 3. Complete clinical baseline data and blood biochemical test results available within two weeks before or after renal biopsy; 4. Complete renal pathology report including Oxford classification (MEST-C) scores.

Exclusion criteria

Exclusion criteria: 1. Secondary IgA nephropathy (e.g., Henoch-Schönlein purpura nephritis, liver cirrhosis, lupus nephritis, diabetic kidney disease, etc.); 2. Patients who received corticosteroids, immunosuppressants, or cytotoxic drugs before renal biopsy; 3. Comorbid malignancy, acute infection, or acute kidney injury; 4. Severe missing clinical or pathological data.

Design outcomes

Primary

MeasureTime frame
Moderate to severe tubulointerstitial fibrosis;—

Countries

China

Contacts

Public ContactLuli Zheng

Fuzhou University Affiliated Provincial Hospital

zhengluli2021@163.com+86 591 88618898

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Jun 11, 2026