Vulnerable plaque (VP) rupture
Conditions
Interventions
Gold Standard:1. Postoperative histopathological diagnosis of carotid endarterectomy (preferred), classifying the target plaques according to the modified AHA criteria into VP and non-VP
2. For those who cannot undergo surgery, the HRMRI interpretation results are used as the reference standard.
Index test:An AI fusion diagnostic model constructed by combining multimodal ultrasound (gray-scale ultrasound, ultrasound viscoelasticity technology, high-frame-rate ultrasound contrast imaging) with
Sponsors
The First Affiliated Hospital of Fujian Medical University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Using the First Affiliated Hospital of Fujian Medical University (Chating/Binhai/Aoti Campus) as the research center, prospectively include patients scheduled for carotid endarterectomy (CEA) or undergoing HRMRI examination.
Exclusion criteria
Exclusion criteria: 1. Age <18 years; 2. Carotid occlusion or stenosis caused by other conditions (e.g., arterial dissection, arteritis); 3. Severe plaque calcification with acoustic shadowing precluding ultrasound assessment; 4. Severe multiple organ failure; 5. Emergency surgery or incomplete imaging/pathological data.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The area under the curve; | — |
Secondary
| Measure | Time frame |
|---|---|
| Sensitivity;Specificity;Decision analysis curve; | — |
Countries
China
Contacts
Public ContactLei Yan
The First Affiliated Hospital of Fujian Medical University
Outcome results
None listed