None
Conditions
Interventions
Fospropofol disodium Group:Anesthesia maintenance using fospropofol disodium
Propfol Group:Anesthesia maintenance using propel
Sponsors
Shanghai Children's Medical Center, School of Medicine, Shanghai Jiao Tong University
Eligibility
Sex/Gender
All
Age
3 Years to 12 Years
Inclusion criteria
Inclusion criteria: 1.Aged 3 to 12 years, of either gender, with a BMI of 18 to 30 kg/m^2; 2. ASA physical status I to II; 3. Requiring elective surgery under general anesthesia, with an estimated operation time of >=60 minutes, and requiring tracheal intubation/laryngeal mask airway, without involving controlled hypotension or other surgeries that may significantly affect the circulatory system; (including but not limited to: urethroplasty in urology, tethered cord release in neurosurgery, selective rhizotomy, arthroscopic exploration and repair in orthopedics, etc.); 4. Family members who can understand the content of this study, are willing to participate, and have signed the informed consent form.
Exclusion criteria
Exclusion criteria: 1.Patients who have previously experienced anesthesia accidents; 2. Patients with abnormal liver function (ALT or AST = 2.5 times the upper limit of normal, TBIL = 1.5 times the upper limit of normal); 3.Patients with abnormal renal function (Cr > upper limit of normal, or undergoing dialysis treatment within 28 days before surgery); 4.Patients with abnormal blood lipids (TC > 170mg/dL; TG > 75mg/dL for ages 3-9, TG > 90mg/dL for ages 10-12); 5.Patients who are allergic to or have contraindications to the trial drug or other anesthetic drugs; 6. Patients who, in the investigator's opinion, have any other factors that make them unsuitable to participate in this trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| BIS;drug dose; | — |
Secondary
| Measure | Time frame |
|---|---|
| HR;Blood pressure;recovery time;additional drug dose;rate of adverse event; | — |
Countries
China
Contacts
Public ContactSiyi Zhou
Shanghai Children's Medical Center, School of Medicine, Shanghai Jiao Tong University, Shanghai
Outcome results
None listed