Obesity
Conditions
Interventions
HFNC oxygen group:Oxygen is delivered via high-flow nasal cannula (HFNC). The oxygen concentration is set to 100%, humidity to 100%, and temperature to 37 °C. After the initiation of anesthesia induct
Mask oxygen group:Oxygen is delivered via a conventional face mask at a routine flow rate of 6 L/min and 100% oxygen concentration. The duration of preoxygenation is no less than 3 minutes.
Sponsors
The Second Affiliated Hospital of Harbin Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1.Age: 18–70 years 2.Obese patients undergoing elective gastric reduction surgery 3.No contraindications to HFNC or mask oxygen therapy 4.BMI >= 32.5 kg/m^2 5.ASA Class I–III 6.No severe cardiopulmonary failure, airway obstruction or other critical illnesses 7.Agree to participate in the study and sign the informed consent
Exclusion criteria
Exclusion criteria: 1.Age 70 years 2.ASA Class IV or higher 3.BMI 55 kg/m^2 4.Severe cardiovascular diseases (ischemic heart disease, heart failure, severe angina, unstable angina or myocardial infarction within 6 months); severe hypertension (SBP > 180 mmHg, DBP > 110 mmHg); hypotension (SBP < 90 mmHg) 5.Severe respiratory diseases (COPD, respiratory failure, asthma, pulmonary bullae, recent upper respiratory tract infection, prior thoracic surgery); hypoxemia (SpO2 < 92%) 6.Severe hepatic and renal disorders 7.Intraoperative change of surgical plan or severe intraoperative complications affecting respiratory function assessment 8.Allergy to active components of sufentanil, remifentanil, propofol injection or medical dressings 9.Contraindications to HFNC, e.g. severe nasal deformity, massive nasal bleeding 10.Failure to cooperate with assessments and follow-up; incomplete data unavailable for machine learning modeling
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of hypoxemia; | — |
Secondary
| Measure | Time frame |
|---|---|
| Baseline characteristics;Preoperative Preoxygenation Assessment;Frequency of intraoperative interventions for SpO2 = 92%;Post-anesthesia Recovery Assessment;Pulmonary complications;Anesthesia time;Surgery time;Extubation time;PACU length of stay;Incidence of unplanned ICU admission;Incidence of unplanned re-intubation;Length of hospital stay;Anesthesia cost;Total hospital cost; | — |
Countries
China
Contacts
Public ContactPeng Pan
The Second Affiliated Hospital of Harbin Medical University
Outcome results
None listed