Perioperative myocardial injury
Conditions
Interventions
taVNS group:Electrical stimulation parameters (frequency: 25 Hz, pulse width: 200 µs) were applied, starting at 10 mA until participants reported a "tingling sensation" within 20 seconds of initiation
control group:Low-stimulation parameters were used, with a current frequency of 1 Hz and a pulse width of 200 µs. The same procedural steps as in the taVNS group were followed.
Sponsors
Jincheng People's Hospital
Eligibility
Sex/Gender
All
Age
65 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Age >=65 years, or age >=45 years with at least one cardiac risk factor (e.g., diabetes mellitus, hypertension, coronary artery disease, etc.); 2. American Society of Anesthesiologists (ASA) physical status classification >= III; 3. Scheduled for abdominal surgery with an expected operative duration >= 120 minutes; 4. Preoperative New York Heart Association (NYHA) functional class I–II; 5. No contraindications to taVNS.
Exclusion criteria
Exclusion criteria: 1. Acute heart failure with NYHA functional class III–IV; 2. History of arrhythmia, myocardial infarction, or coronary artery bypass grafting; 3. Auricular deformity, infection, or skin damage precluding auricular stimulation; 4. Cognitive impairment interfering with completion of scale assessments; 5. Allergy to materials of the stimulation device.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| hs-cTnI;Perioperative Neurocognitive Disorders;HRV;Inflammatory factors (C-reactive protein and IL-6).; | — |
Secondary
| Measure | Time frame |
|---|---|
| length of stay (LOS);Perioperative Sleep Quality;nausea and vomiting;Postoperative recovery of gastrointestinal function;Quality of postoperative recovery;the satisfaction of patients;Postoperative pain score; | — |
Countries
China
Contacts
Public ContactLi Luyao; Wang Jinping
Jincheng People's Hospital
Outcome results
None listed