None
Conditions
Interventions
Control group:An equal volume of normal saline was infused instead.
Sponsors
Shengjing Hospital, China Medical University
Eligibility
Sex/Gender
All
Age
3 Years to 14 Years
Inclusion criteria
Inclusion criteria: 1.Patients aged 3–14 years; 2.Scheduled to undergo elective surgery under general anesthesia; 3.Expected duration of surgery of 1 hour or longer; 4.American Society of Anesthesiologists (ASA) physical status I or II; 5.Voluntary signed informed consent.
Exclusion criteria
Exclusion criteria: Exclusion criteria were as follows: 1.Developmental disabilities, history of neurological diseases or psychiatric disorders; 2.Severe cardiopulmonary dysfunction; hepatic or renal dysfunction; endocrine dysfunction; 3.Respiratory tract infection within one week; 4.Experienced significant stress or major life events within one month (e.g., parental divorce, other trauma or illness, etc.); 5.Patients expected to require postoperative admission to the ICU; 6.Known allergy to the active ingredient of sodium oxybate injection, or presence of contraindications to sodium oxybate use, such as hypokalemia, ethanol intoxication, or severe cardiac dysfunction, etc.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pediatric Anesthesia Emergence Delirium(PAED) score for emergence agitation;Cornell Assessment of Pediatric Delirium(C-CAPD) Score for Postoperative Delirium; | — |
Secondary
| Measure | Time frame |
|---|---|
| FLACC Pain Scale Score for Assessment;Pediatric Scale for Quality of Recovery,PedSQoR;Self-Rating Sleep Scale Score for Sleep Quality;Children's Modified Yale Preoperative Anxiety Scale(CM-YPAS)for Anxiety;Perioperative Respiratory Adverse Events;Ramsay Score;Mask Acceptance Scale (MAS) for evaluating tolerance to facemask induction;Induction Compliance Checklist (ICC);Richmond Agitation-Sedation Scale;Postoperative inflammatory markers(IL-6,CRP); | — |
Countries
China
Contacts
Public ContactPing Zhao
Shengjing Hospital of China Medical University
Outcome results
None listed