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Effect of Ciprofol on Postoperative Delirium in Elderly Patients Undergoing Gastrointestinal Tumor Surgery: A Prospective Randomized Controlled Trial

Effect of Ciprofol on Postoperative Delirium in Elderly Patients Undergoing Gastrointestinal Tumor Surgery: A Prospective Randomized Controlled Trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600125770
Enrollment
Unknown
Registered
2026-05-31
Start date
2026-05-31
Completion date
Unknown
Last updated
2026-06-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

tumor

Interventions

P group:Intravenous injection of ciprofol
C group:Intravenous injection of propofol

Sponsors

The Fourth Hospital of Hebei Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
65 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Age range: 65 - 80 years old; Body Mass Index (BMI) within 18 kg/m^2 to 30 kg/m^2; 2. Patients willing to undergo total intravenous anesthesia; 3. Voluntary participants in this study and having signed the informed consent form; 4. Capable of completing the cognitive assessment scale and related clinical follow-up; 5. Preoperative Mini-Mental State Examination (MMSE) score >= 27 points; 6. American Society of Anesthesiologists (ASA) classification of grades I to III.

Exclusion criteria

Exclusion criteria: 1. Patients who are allergic to the anesthetic drugs used in this study; 2. Patients with a history of alcohol, sedative-hypnotic drugs, psychotropic drugs, or drug abuse and addiction; 3. Patients with a history of stroke, transient ischemic attack, or traumatic brain injury; 4. Patients who refuse to participate in the study.

Design outcomes

Primary

MeasureTime frame
The incidence of postoperative POD in the two groups;

Secondary

MeasureTime frame
Pain score;Incidence of anesthesia-related adverse reactions;

Countries

China

Contacts

Public ContactHuaqin Liu

The Fourth Hospital of Hebei Medical University

liuhuaqin@hebmu.edu.cn+86 185 3111 8952

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Jun 11, 2026