tumor
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Age range: 65 - 80 years old; Body Mass Index (BMI) within 18 kg/m^2 to 30 kg/m^2; 2. Patients willing to undergo total intravenous anesthesia; 3. Voluntary participants in this study and having signed the informed consent form; 4. Capable of completing the cognitive assessment scale and related clinical follow-up; 5. Preoperative Mini-Mental State Examination (MMSE) score >= 27 points; 6. American Society of Anesthesiologists (ASA) classification of grades I to III.
Exclusion criteria
Exclusion criteria: 1. Patients who are allergic to the anesthetic drugs used in this study; 2. Patients with a history of alcohol, sedative-hypnotic drugs, psychotropic drugs, or drug abuse and addiction; 3. Patients with a history of stroke, transient ischemic attack, or traumatic brain injury; 4. Patients who refuse to participate in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence of postoperative POD in the two groups; | — |
Secondary
| Measure | Time frame |
|---|---|
| Pain score;Incidence of anesthesia-related adverse reactions; | — |
Countries
China
Contacts
The Fourth Hospital of Hebei Medical University