Locally advanced esophageal squamous cell carcinoma and non-small cell lung cancer
Conditions
Interventions
Intervention Group:Comprehensive Health Support Intervention
Sponsors
Hunan Cancer Hospital
Eligibility
Sex/Gender
All
Age
15 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1.Aged 18 to 75 years; 2.Pathologically confirmed esophageal squamous cell carcinoma or non-small cell lung cancer, scheduled to undergo radical surgery after neoadjuvant chemo-immunotherapy; 3.Able to read and understand the study materials and complete questionnaires independently; 4.Able to comply with study procedures, follow-up, assessments, and interventions; 5.Normal limb function and considered safe for preoperative and postoperative exercise intervention after cardiopulmonary evaluation; 6.No obvious exercise limitation and suitable for individualized exercise intervention, including aerobic and resistance training; 7.Voluntarily agree to participate and sign informed consent.
Exclusion criteria
Exclusion criteria: 1.Patients unsuitable for body composition analysis, such as those with pacemakers, metallic implants, or postoperative drainage tubes; 2.Severe or uncontrolled systemic diseases that may significantly affect the risk-benefit balance; 3.Pregnant or breastfeeding women; 4.Cognitive impairment or psychiatric abnormalities preventing study participation and follow-up; 5.Metastasis to other major organs making R0 resection impossible; 6.Concomitant malignancy at another site; 7.Severe postoperative complications making exercise intervention intolerable; 8.Failure to complete the exercise program/intervention due to poor compliance or exercise-related adverse reactions; 9.Other conditions considered unsuitable by the investigator. 10. Individuals with severe cardiovascular, respiratory, or other underlying diseases, who are assessed as unsuitable for preoperative or postoperative exercise intervention;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative complication rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Cardiopulmonary function; | — |
Countries
China
Contacts
Public ContactYang De Song
Hunan Cancer Hospital
Outcome results
None listed