cognitive frailty
Conditions
Interventions
Post-stroke cognitive impairment control group:Medication and conventional rehabilitation therapy (muscle strength training, range of motion training, gait training, balance function training, cogniti
Post-stroke cognitive impairment hyperbaric oxygen therapy group:Medication and conventional rehabilitation therapy (muscle strength training, range of motion training, gait training, balance function
Sponsors
Shanghai Pudong New Area People’s Hospital
Eligibility
Sex/Gender
All
Age
40 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Age between 40 and 75 years; 2. Stroke patients with cognitive impairment, MoCA score < 26; 3. First-ever hemorrhagic or ischemic stroke confirmed by neuroimaging; 4. The patient is conscious and has stable vital signs; 5. The patient or their legal guardian agrees and signs the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Individuals with transient ischemic attacks with reversible neurological deficits or multiple strokes with other secondary changes. 2. Individuals with multiple cerebral hemorrhagic lesions. 3. Individuals with stroke combined with primary diseases of the hematopoietic system, liver and kidney systems, or endocrine system. 4. Individuals with hydrocephalus, recurrent strokes, or other neurodegenerative diseases (such as Alzheimer's disease, Parkinson's disease, ALS, multiple sclerosis). 5. Individuals with a history of seizures, undergoing thrombolytic therapy, chronic obstructive pulmonary disease with CO2 retention, pneumothorax, intestinal obstruction, sickle cell disease, arrhythmia, claustrophobia, blood pressure >180/120 mmHg, or other heart diseases combined with atrial fibrillation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cognitive function assessment;Stroke Recurrence Risk Assessment;Imaging Assessment of Cognitive Function;Blood-Based Biochemical Marker Testing for Cognitive Function;Lipidomics Analysis; | — |
Secondary
| Measure | Time frame |
|---|---|
| General Data Collection and Examination;Blood Glucose and Lipid Profile (Four Items); | — |
Countries
China
Contacts
Public ContactJingyun Hu
Shanghai Pudong New Area People’s Hospital
Outcome results
None listed