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Efficacy validation of transcranial focused ultrasound for cognitive impairment in post-stroke patients: a near-infrared brain imaging study

Efficacy validation of transcranial focused ultrasound for cognitive impairment in post-stroke patients: a near-infrared brain imaging study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600125703
Enrollment
Unknown
Registered
2026-05-29
Start date
2026-05-29
Completion date
Unknown
Last updated
2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Post-stroke cognitive impairment

Interventions

Experimental group:Transcranial focused ultrasound combined with conventional cognitive rehabilitation training
Control group:Conventional cognitive rehabilitation training

Sponsors

Beijing Rehabilitation Hospital,Capital Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. The diagnosis of stroke complies with "Key Points for Diagnosis of Major Cerebrovascular Diseases in China 2019", and is confirmed by head CT or MRI examination; 2. The diagnosis of PSCI complies with the diagnostic criteria of "Expert Consensus on the Management of Post-stroke Cognitive Impairment 2021"; 3. Age is between 18 years and 80 years (inclusive), and gender is not restricted; 4. The disease course is from 2 weeks to 6 months after stroke; 5. The patient or their guardian has signed the research informed consent form; 6. MMSE score: 10 < MMSE < 26.

Exclusion criteria

Exclusion criteria: 1. Patients with cognitive dysfunction caused by non-stroke conditions such as brain trauma and Alzheimer's disease; 2. Patients with skull defects or having implanted metal in the brain; 3. Patients with implanted electronic devices (such as cardiac pacemakers); 4. Patients with bleeding tendencies and elevated intracranial pressure; 5. Pregnant patients; 6. Patients with visual and language impairments; 7. Patients with severe heart diseases or other internal medical conditions.

Design outcomes

Primary

MeasureTime frame
Mini-mental state examination;Montreal cognitive assessment;

Secondary

MeasureTime frame
Stroke-Specific Depression Scale;

Countries

China

Contacts

Public ContactWang Congxiao

Beijing Rehabilitation Hospital,Capital Medical University

wangcongxiao66@163.com+86 189 1033 7178

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Jun 11, 2026