A Prospective Cohort Study on the Impact of Different Human-Machine Collaborative Weight Management Models on Outcomes in Obese Adults in a Real-World Community Setting

Real-world Research on Chronic Disease Population: Model Construction and Digital Intelligent Management

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2600125680

Enrollment

Unknown

Registered

2026-05-29

Start date

2026-06-01

Completion date

Unknown

Last updated

2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Obesity

Interventions

Self-management group:None

Patient + patient-AI management group:None

Patient + patient-AI + physician management group:None

Patient + patient-AI + physician + physician-AI management grou:None

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Aged >=18 years. 2. Confirmed obesity, meeting any one of the following criteria: Body mass index (BMI) >=28 kg/m²; Or meeting one of the criteria for high body fat/central obesity: waist circumference >90 cm in males, >85 cm in females; waist-to-hip ratio >=0.90 in males, >=0.85 in females; waist-to-height ratio >=0.50; body fat percentage >25% in males, >30% in females. 3. Receiving one of the four weight management models in the real community clinical setting during the study period: patient self-management, physician-led management in weight loss clinics, AI-enabled patient management, AI-enabled physician management. 4. Able to complete physical measurements, laboratory tests and questionnaires at baseline and the 3-month follow-up. 5. Understand the study content and voluntarily sign the informed consent form. 6. Able to use a smartphone to complete platform records, or complete electronic questionnaires and follow-up with the assistance of researchers.

Exclusion criteria

Exclusion criteria: 1. Pregnant or lactating women, or those planning pregnancy within 3 months. 2. Secondary obesity with unstable underlying causes. 3. Undergoing bariatric surgery within the past 6 months. 4. Severe impairment of cardiac, hepatic, renal or other vital organ function, or unsuitable for lifestyle intervention. 5. Severe mental disorder or cognitive impairment, unable to provide informed consent or complete follow-up. 6. Participation in other weight-affecting intervention studies at baseline. 7. Judged ineligible by the investigator.

Design outcomes

Primary

Measure	Time frame
Percentage of weight change;	—

Secondary

Measure	Time frame
Body Mass Index (BMI);waist circumference;Proportion of subjects with >=5% weight loss;follow-up compliance;	—

Countries

China

Contacts

Public ContactWenhong Zhang

Nanjing University Medical School

whzhang@nju.edu.cn+86 25 8359 1175

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Jun 11, 2026