Breast cancer treated with neoadjuvant therapy
Conditions
Interventions
Observation group:None
Sponsors
The First Affiliated Hospital of Chongqing Medical University
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1.Patients with primary breast cancer confirmed by histopathology. 2.Patients who received standard neoadjuvant therapy and subsequent surgery at the First Affiliated Hospital of Chongqing Medical University. 3.Availability of pre-treatment core needle biopsy pathology and post-operative pathology specimens. 4.Pathological complete response (pCR), Miller-Payne (MP) grade, and postoperative pathological lymph node status (ypN) could be evaluated.
Exclusion criteria
Exclusion criteria: 1.Patients with distant metastasis at initial diagnosis; 2.Patients who did not undergo surgery after planned neoadjuvant therapy; 3.Patients with missing key outcome data and unevaluable treatment response; 4.Patients lacking essential paired pathological data before and after treatment for dynamic analysis; 5.Duplicate cases or cases with incomplete key information after verification;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Conversion rates of ER, PR, and HER2; | — |
Secondary
| Measure | Time frame |
|---|---|
| Dynamic change in AR;Dynamic change in Ki-67; | — |
Countries
China
Contacts
Public ContactLiu Shengchun
The First Affiliated Hospital of Chongqing Medical University
Outcome results
None listed