Postoperative Sleep in Elderly Non-Cardiac Surgery Patients
Conditions
Interventions
Experimental group:100 µg of dexmedetomidine nasal spray was administered in the anesthesia preparation room before surgery
Control group:administer the same volume of saline nasal spray in the anesthesia preparation room before surgery,
Sponsors
The First Affiliated Hospital of Dalian Medical University
Eligibility
Sex/Gender
All
Age
60 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Age >= 60 years; 2. ASA class II-III; 3. Planned non-cardiac surgery; 4.BMI 18-30 kg/m^2; 5.Signed informed consent; 6.Patients receiving a pain pump;
Exclusion criteria
Exclusion criteria: 1. Patients allergic to drugs used during the study; 2. Patients with sick sinus syndrome, severe sinus bradycardia (heart rate =3 and HCO3- >=28 mmol/L; 4. Patients unsuitable for nasal spray administration, such as those with severe rhinitis; 5. Patients with cognitive impairment or unable to communicate; 6. Patients with severe hepatic dysfunction (Child-Pugh class C) or severe renal dysfunction (on dialysis before surgery); 7. Patients unable to sit upright.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence of sleep disturbance on the first postoperative night.; | — |
Secondary
| Measure | Time frame |
|---|---|
| Hemodynamic parameters;Adverse reactions;Fitbit Charge 4 assessment of sleep quality;Opioid consumption;Restore quality score;NRS Pain Score;Anxiety Score;Delirium Assessment;Rescue analgesia; | — |
Countries
China
Contacts
Public ContactChunmei Wang
The First Affiliated Hospital of Dalian Medical University
Outcome results
None listed