Major Mental Disorders
Conditions
Interventions
Retrospective cohort:None
Prospective cohort:None
Sponsors
West China Hospital, Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Patients aged 18-65 years with a clinical diagnosis of major mental disorders (e.g., schizophrenia, bipolar disorder, depression, and anxiety disorders); 2. Patients who are able to provide complete neuroimaging, molecular biological data, and questionnaire-based assessments.
Exclusion criteria
Exclusion criteria: 1. Presence of severe physical illnesses that may affect mental status. 2. Any contraindications to magnetic resonance imaging (MRI), including but not limited to claustrophobia, metallic implants, or other conditions that preclude completion of the full MRI examination.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Brain volume Z scores;Discordance of admission and discharge diagnosis;Rehospitalization rate;Positive And Negative Syndrome Scale, PANSS;Global Assessment of Functioning,GAF;Brief Assessment of Cognition in Schizophrenia, BACS; | — |
Countries
China
Contacts
Public ContactSu Lui
West China Hospital of Sichuan University
Outcome results
None listed