Preconception genetic screening for couples planning to have children
Conditions
Interventions
Observational group:None
Sponsors
Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Couples planning pregnancy or with a gestational age of 28 weeks or less; 2. Voluntarily participate in this study and sign an informed consent form.
Exclusion criteria
Exclusion criteria: 1. Couples intending to use donated gametes for reproduction; 2. Those who have received blood transfusions, organ transplants, or immunotherapy within the past year; 3. Spouses unable to cooperate with testing; 4. Vulnerable groups other than pregnant women, including people with mental illness, cognitive impairment, critically ill patients, minors, and the illiterate.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Carrier rate in couples;Detection rate in high-risk couples;Variant carrier rate;Gene carrier rate;Reproductive outcomes; | — |
Countries
China
Contacts
Public ContactJin Jiamin
Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University
Outcome results
None listed