Thyroid cancer
Conditions
Interventions
Control group:Mivacurium continuous infusion is not used during the maintenance phase of anesthesia
Experimental group:Continuous infusion of mivacurium was used during the maintenance phase of anesthesia
Sponsors
Shenshan Medical Center, Sun Yat-sen Memorial Hospital, Sun Yat-sen University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1.Patients aged 18 to 65 years, ASA I-II, undergoing elective thyroid surgery; 2.Intraoperative neurophysiological monitoring was used; 3.No history of severe allergy to mikukloramine or other foods and drugs, or allergic diseases; 4.The patient voluntarily participates and has signed the informed consent form.
Exclusion criteria
Exclusion criteria: 1.Body mass index (BMI) 30 kg/m^2; 2.SBP > 180 mmHg or DBP > 110 mmHg; 3.Those with a history of asthma or other severe allergic conditions; 4.Those with neuromuscular junction diseases such as Parkinson's and myasthenia gravis; 5.Known or suspected atypical plasma cholinesterase gene homozygotes and decreased plasma cholinesterase; 6.Pregnant and breastfeeding women; 7.The patient is generally in poor condition, with a medical history of severe cardiovascular, respiratory, liver and kidney, central nervous system, and hematological diseases. 8.People who abuse alcohol or rely on painkillers or psychiatric medications; 9.Concurrent use of contraindicated drugs
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Satisfaction with the surgery;Conditions for tracheal intubation;Depth of anesthesia; | — |
Secondary
| Measure | Time frame |
|---|---|
| Adverse reaction;Awakening-related indicators; | — |
Countries
China
Contacts
Public ContactLiu Ling
Sun Yat-sen Memorial Hospital, Sun Yat-sen University
Outcome results
None listed