Myopia
Conditions
Interventions
Group 1:Prescribed optical zone size of 6.0 mm for excimer laser refractive surgery (LASIK)
Group 2:Prescribed optical zone size of 6.5 mm for excimer laser refractive surgery (LASIK)
Sponsors
Hangzhou MSK Eye Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: 1.Aged 18–45 years of either gender; good general physical condition without severe systemic diseases involving the heart, liver, kidney, endocrine system and other systems. 2.Diagnosed with moderate to high hyperopia by comprehensive preoperative refraction; spherical refraction >= +3.00 D with stable refractive status (refractive change = 480 µm with normal corneal topography; no corneal diseases such as keratitis, corneal ulcer, keratoconus, etc. 4.No history of ocular surgery or ocular trauma; no other ocular diseases including glaucoma, cataract, uveitis and so on. 5.No contraindications to excimer laser surgery (e.g., dry eye syndrome, scar diathesis, autoimmune diseases, etc.). 6.All patients provided informed consent, voluntarily participated in this study, and were able to cooperate with preoperative examinations, surgical procedure and 6-month postoperative follow-up.
Exclusion criteria
Exclusion criteria: 1.Age younger than 18 years or older than 45 years; unstable refractive status (refractive change > 0.50 D within the past one year). 2.Spherical refraction less than +3.00 D. 3.Corneal thickness less than 480 µm, or with abnormal corneal topography or corneal diseases. 4.Having a history of ocular surgery or ocular trauma, or complicated with ocular diseases such as glaucoma, cataract, uveitis and retinopathy. 5.Having contraindications to excimer laser surgery, or complicated with systemic diseases (such as diabetes, autoimmune diseases, scar diathesis, etc.). 6.Unable to cooperate with preoperative examination, surgery or postoperative follow-up, or refusing to sign the informed consent form. 7.Preoperative presence of severe dry eye, anisometropia (interocular refractive difference > 2.00 D) and other factors affecting postoperative visual evaluation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Visual acuity and higher-order aberrations at 1, 3, and 6 months postoperatively; | — |
Secondary
| Measure | Time frame |
|---|---|
| Refraction correction efficacy: uncorrected visual acuity (UCVA), best-corrected visual acuity (BCVA), and refractive status at 1, 3, and 6 months postoperatively;Corneal-related parameters: corneal topography at 1, 3, and 6 months postoperatively;Incidence of complications: glare, halos, dry eye, delayed corneal epithelial healing, corneal infection, etc.;Baseline characteristics correlation: association between patient age, preoperative refractive error, corneal thickness, and postoperative visual quality; | — |
Countries
China
Contacts
Public ContactZhang Jun
Hangzhou MSK Eye Hospital
Outcome results
None listed