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The effect of intermittent theta pulse stimulation on the post-traumatic consciousness disorder of patients with brain injury

The effect of intermittent theta pulse stimulation on the post-traumatic consciousness disorder of patients with brain injury

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600125620
Enrollment
Unknown
Registered
2026-05-28
Start date
2026-06-01
Completion date
Unknown
Last updated
2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

The post-traumatic consciousness disorder of patients with brain injury

Interventions

Intervention group:ITBs group stimulated the left dorsolateral prefrontal cortex
Control group:Conventional treatment

Sponsors

Fuyang People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: 1.Those who meet the diagnostic criteria for severe craniocerebral injury and DOC, diagnosed through clinical manifestations, CT or MRI imaging examinations as craniocerebral injury; 2.The cause of coma is craniocerebral injury, evaluated by GCS and CRS-R; 3.The level of consciousness disorder is in the vegetative state (VS) or unresponsive wakefulness syndrome (UWS) stage; 4.The course of craniocerebral injury is within half a year and the condition is stable; 5.Age between 18 and 80 years old; 6.No hearing impairment before the onset; 7.The direct family members give informed consent and sign the informed consent form.

Exclusion criteria

Exclusion criteria: Exclusion criteria: 1.Patients with unstable condition or severe pneumonia in critical condition; 2.Those with implanted electronic devices or metal objects in the brain; 3.Those with severe bullae in the lungs or active pneumothorax; 4.Those with a history of epilepsy; 5.Those with left frontal skull defect; 6. Family members who refuse to allow participation.

Design outcomes

Primary

MeasureTime frame
Brainstem auditory evoked potential, BAEP;

Secondary

MeasureTime frame
Glasgow Coma Scale Score, GCS;Modified Coma Recovery Scale Score,CRS-R;

Countries

China

Contacts

Public ContactQiao Kangxi

Fuyang People's Hospital

qkx18326802593@163.com+86 183 2680 2593

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Jun 11, 2026