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Development of a Standard Operating Procedure for Perioperative Blood Glucose Management in Patients With Type 2 Diabetes Undergoing Colorectal Endoscopic Submucosal Dissection

Development of a Standard Operating Procedure for Perioperative Blood Glucose Management in Patients With Type 2 Diabetes Undergoing Colorectal Endoscopic Submucosal Dissection

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600125612
Enrollment
Unknown
Registered
2026-05-28
Start date
2026-06-01
Completion date
Unknown
Last updated
2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Type 2 diabetes mellitus

Interventions

Control group:The patient will undergo the current routine perioperative blood glucose management. This includes: standard bowel preparation instructions, blood glucose monitoring as directed by the d
Trial group:Based on routine care, the "SOP for Blood Glucose Management during the Perioperative Period of Non-Painful Colorectal ESD in Type 2 Diabetic Patients" constructed by this study was implem
preventive glucose supplementation at multiple time points (administer 20 ml of 50% glucose injection orally when the blood glucose monitoring value is 3.9–5.6 mmol/L, and recheck 15 minutes later
the target blood glucose should be 5.6–10.0 mmol/L
for 2 hours before the operation, glucose was supplemented through intravenous infusion)
acupoint massage and walking activity guidance
targeted assessment and counseling for hypoglycemia fear.

Sponsors

Peking University First Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Diagnosed with type 2 diabetes according to the "Standards of Medical Care in Diabetes" published by the American Diabetes Association (ADA) in 2025; 2. Age >=18 years; 3. Patients undergoing elective painless endoscopic submucosal dissection (ESD) for colorectal lesions; 4. Capable of effective communication and comprehension, mentally alert, mentally stable, able to understand questionnaire content and answer questions, capable of understanding the study details, willing to participate voluntarily, and able to sign a written informed consent form; 5. Able to follow the standard bowel preparation protocol.

Exclusion criteria

Exclusion criteria: 1. Patients with coronary heart disease, old myocardial infarction, renal insufficiency, shock, ascites; 2. Patients with gastrointestinal obstruction or suspected obstruction, intestinal perforation, gastric retention, gastrointestinal bleeding, toxic enteritis or toxic megacolon, intestinal diverticulum, severe ulcerative colitis; 3. Severe depression, schizophrenia; 4. Sensory or cognitive impairments, such as severe hearing impairment, dementia, inability to cooperate in completing the questionnaire or intervention measures; 5. Pregnant or lactating women; 6. Those known to be allergic to the components of the study drug; 7. Those planning to use non-standard intestinal preparation methods; 8. Glycated hemoglobin > 8%.

Design outcomes

Primary

MeasureTime frame
Incidence of perioperative hypoglycemia;

Secondary

MeasureTime frame
Standard deviation of blood sugar;Blood glucose coefficient of variation;Fear score of hypoglycemia;Intestinal cleansing rate;Incidence of perioperative hyperglycemia;

Countries

China

Contacts

Public ContactDeng Hongce

Peking University First Hospital

tb0004307_2011@163.com+86 10 5695 7116

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Jun 11, 2026