periorbital wrinkles
Conditions
Interventions
Left side:Low-power long-pulse-width treatment method
Right side:High-power short-pulse-width treatment method
Sponsors
Huashan Hospital, Fudan University
Eligibility
Sex/Gender
All
Age
25 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1.Patients with periorbital wrinkles, with a Fitzpatrick wrinkle score of more than 3, aged between 25 and 65 years, regardless of gender. 2.Periorbital wrinkles have never undergone any other treatments. 3.After fully understanding the treatment plan and its risks, the individual or the guardian voluntarily signs the informed consent form, willing to participate in the self-controlled trial and cooperate with the follow-up.
Exclusion criteria
Exclusion criteria: 1.Pregnant women or women planning to conceive; 2.Those with severe dysfunction of the heart, liver and kidneys, autoimmune diseases, mental disorders or other major disorders of the body systems; 3.There are skin diseases such as traumatic, open wounds, suppurative wounds and active inflammatory herpes in the treatment area. 4.For those who are allergic to topical anesthetics or microneedle materials; 5.Patients currently participating in other clinical trials; 6.The treatment area has received phototherapy, injections, surgeries, etc. within the past one year. 7.Taking glucocorticoids or other immunosuppressants, or anticoagulants within one month; 8.The researchers considered those participants who were not suitable for the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| severity of periorbital wrinkles; | — |
Secondary
| Measure | Time frame |
|---|---|
| Periorbital Wrinkles Area;severity and morphology of periorbital wrinkles;Subject satisfaction;TEWL; | — |
Countries
China
Contacts
Public ContactLU Zhong
Huashan Hospital, Fudan University
Outcome results
None listed