Major Depressive Disorder (with or without psychotic features) and Bipolar and Related Disorders
Conditions
Interventions
Sponsors
Peking University Sixth Hospital ( Institute of Mental Health )
Eligibility
Sex/Gender
All
Age
12 Years to 17 Years
Inclusion criteria
Inclusion criteria: 1.Aged 12–17 years; 2.No gender restriction; 3.Diagnosis confirmed by a child psychiatrist using the Chinese version of the Kiddie Schedule for Affective Disorders and Schizophrenia for School-Age Children – Present and Lifetime version (C-K-SADS-PL) semi-structured interview, meeting one of the following diagnostic criteria: Major Depressive Disorder without psychotic features, Major Depressive Disorder with psychotic features, or Bipolar and Related Disorders; 4.Both the participant and their legal guardian voluntarily agreed to participate in the study and signed written informed consent.
Exclusion criteria
Exclusion criteria: 1.Presence of a serious somatic disease or neurological disorder that may significantly affect the assessment of psychiatric symptoms; 2.Other severe mental disorders (e.g., schizophrenia) that interfere with the primary diagnosis; 3.Significant cognitive, language, or behavioral impairments that preclude completion of standardized assessments or long-term follow-up;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| World Health Organization Disability Assessment Schedule, WHODAS; | — |
Secondary
| Measure | Time frame |
|---|---|
| Connor-Davidson Resilience Scale Score, CD-RISC;Mood Disorder Questionnaire, MDQ;Family Assessment Device Score, FAD;3.0 Tesla Magnetic Resonance Imaging;Hamilton Depression Rating Scale-17 item Score, HAMD-17;Beck Hopelessness Scale Score, BHS;Depression Self-Rating Scale for Children Score, DSRSC;Positive and Negative Suicide Ideation Inventory Score, PANSI;Clinical Global Impression Scale, CGI;Young Mania Rating Scale, YMRS;Chinese version of the Kiddie Schedule for Affective Disorders and Schizophrenia for School-Age Children-Present and Lifetime version, C- K-SADS-PL; | — |
Countries
China
Contacts
Public ContactQingjiu Cao
Peking University Sixth Hospital ( Institute of Mental Health )
Outcome results
None listed