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Therapeutic Effect of Dual-Approach Intercostal Nerve Block Combined with Pulsed Radiofrequency on Herpes Zoster-Related Pain

Therapeutic Effect of Dual-Approach Intercostal Nerve Block Combined with Pulsed Radiofrequency on Herpes Zoster-Related Pain

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600125587
Enrollment
Unknown
Registered
2026-05-28
Start date
2026-06-05
Completion date
Unknown
Last updated
2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Herpes Zoster-Associated Neuralgia

Interventions

Experimental Group (Group I):The radiofrequency cannula was first punctured to the vicinity of the intervertebral foramen at the corresponding segment. After negative blood and cerebrospinal fluid asp
Experimental Group (Group T):The radiofrequency cannula was punctured to the vicinity of the intervertebral foramen at the corresponding segment. After aspiration yielded no blood or cerebrospinal flu
each cycle lasted 30 seconds, with a total of 12 cycles. Subsequently, paravertebral nerve block was performed. The compound analgesic solution was composed of 2% lidocaine 5 mL, dipro

Sponsors

Affiliated Hospital of Xuzhou Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Patients aged 18 years or older who meet the ZAP diagnostic criteria 2. Disease duration = 4 points 6. Able to cooperate with follow-up and undergo nerve block and radiofrequency procedures as required

Exclusion criteria

Exclusion criteria: 1.Patients with hemorrhagic diseases or coagulation disorders. 2.Patients with unclear etiology of pain or combined with other types of chronic pain. 3.Active infection or skin damage at the puncture site. 4.Severe cardiopulmonary dysfunction. 5.Mental disorders or communication disorders. 6.Patients who have received similar radiofrequency or nerve block interventions in the observed area previously. 7.Those who voluntarily withdraw from the study or are lost to follow-up. 8.Those who receive other treatments that may affect the efficacy of ZAP without authorization during the follow-up period. 9.Cases with intervention failure or incorrect operative approach. 10.Cases with interrupted evaluation due to the occurrence of serious adverse events.

Design outcomes

Primary

MeasureTime frame
NRS pain score;

Secondary

MeasureTime frame
Generalized Anxiety Disorder 7-item Scale;Pittsburgh Sleep Quality Index;Patient Health Questionnaire-9;Von Frey filament mechanical pain threshold;Adverse events;

Countries

China

Contacts

Public ContactYin Qin

The Affiliated Hospital of Xuzhou Medical University

810780794@qq.com+86 138 1444 6826

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Jun 11, 2026