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Analysis of Renal Clear Cell Carcinoma Heterogeneity and Prognostic Prediction Based on Multiscale Topological Isomerism of CT Images: A Multicenter Study

Analysis of Renal Clear Cell Carcinoma Heterogeneity and Prognostic Prediction Based on Multiscale Topological Isomerism of CT Images: A Multicenter Study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600125581
Enrollment
Unknown
Registered
2026-05-28
Start date
2026-05-31
Completion date
Unknown
Last updated
2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Clear cell renal cell carcinoma

Interventions

Postoperative recurrence with metastasis
postoperative absence of recurrence or metastasis:none

Sponsors

The First Affiliated Hospital of Nanchang University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Patients who underwent renal space-occupying lesion resection at tertiary hospitals and were pathologically diagnosed with renal clear cell carcinoma; 2. Presence of at least one high-recurrence risk factor: multiple nodular tumors (>=2), maximum tumor diameter >5 cm, associated satellite nodules, concurrent large-vessel tumor thrombus, or poor pathological differentiation (grades III–IV).

Exclusion criteria

Exclusion criteria: 1. Pathologically confirmed non-clear cell renal cell carcinoma; 2. Concurrent extrarenal metastases or other malignant tumors; 3. Concurrent severe organ failure of the heart, lungs, brain, kidneys, etc. 4. Prior preoperative antitumor therapy for renal clear cell carcinoma.

Design outcomes

Primary

MeasureTime frame
High and low ITH scores;Area Under the Receiver Operating Characteristic Curve (AUC);Accuracy;Precision;Recall ;

Countries

China

Contacts

Public ContactTan Yongming

The First Affiliated Hospital of Nanchang University

ndyfy04394@ncu.edu.cn+86 791 8869 9383

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Jun 11, 2026