major depressive disorder
Conditions
Interventions
Healthy Control Group:None
Sponsors
The First Affiliated Hospital of University of South China
Eligibility
Sex/Gender
All
Age
12 Years to 18 Years
Inclusion criteria
Inclusion criteria: 1. DD Group (Depressive Disorder Group): (1) Aged 12–18 years, male or female. (2) Meet the diagnostic criteria for depressive disorder according to DSM-5, with a total score of =7 on the 17-item Hamilton Depression Rating Scale (HAMD-17). (3) The patient voluntarily participates in this study, and both the patient and their legal guardian have signed the written informed consent form. 2. HC Group (Healthy Control Group): (1) Aged 12–18 years, male or female. (2) Total score <7 on the 17-item Hamilton Depression Rating Scale (HAMD-17). (3) No prior history of any mental illness. (4) The subject voluntarily participates in this study, and both the subject and their legal guardian have signed the written informed consent form.
Exclusion criteria
Exclusion criteria: (1) Presence of severe physical illness. (2) Previous history of mental illness. (3) Presence of cognitive impairment, hearing, visual, or intellectual disabilities that prevent cooperation in completing the 17-item Hamilton Depression Rating Scale (HAMD-17) assessment. (4) Women who are pregnant or breastfeeding. (5) Individuals with drug abuse or alcohol dependence. (6) Participation in a related clinical trial within the past 3 months. (7) Any other conditions that, in the investigator's opinion, make the subject unsuitable for participation in the clinical study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 17-Item Hamilton Depression Rating Scale Score;electrocardiogram;electroencephalogram;systolic blood pressure;diastolic blood pressure;heart rate; | — |
Countries
China
Contacts
Public ContactHuifang Tang
The First Affiliated Hospital of University of South China
Outcome results
None listed