Advanced gastric cancer
Conditions
Interventions
ß-blocker exposed group:None
ß-blocker unexposed group:None
Sponsors
Southern Medical University Southern Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1. Age between 18 and 85 years old; 2. No gender restrictions; 3. Patients whose primary gastric lesions are pathologically diagnosed as gastric adenocarcinoma by endoscopic biopsy according to the 15th edition of the Japanese Gastric Cancer Treatment Guidelines (2017); 4. Patients who underwent gastrectomy after receiving neoadjuvant immunochemotherapy combined with immunotherapy at Nanfang Hospital of Southern Medical University and other sub-center hospitals from April 2021 to September 2025;
Exclusion criteria
Exclusion criteria: 1.Pregnant or lactating women; 2.Severe mental illness; 3.Patients with a history of chemotherapy, radiotherapy, or targeted drug therapy; 4.History of other malignant tumors within the past 5 years; 5.Patients with active infection, active or refractory autoimmune diseases, or uncontrolled systemic diseases; 6.Deemed by the researcher to be unsuitable to participate in this study;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Indicators Related to Tumor Regression in the Experimental Group;Control group tumor regression-related indicators; | — |
Secondary
| Measure | Time frame |
|---|---|
| The 3-year overall survival and relapse-free survival of patients in the experimental group;The starting time, duration, type of drug, and dosage of beta-blockers;The start time, duration, type, and dosage of antihypertensive drugs such as ACEI/ARB/CCB/diuretics; for those not taking medication, record the observation time;The 3-year overall survival and relapse-free survival of patients in the control group; | — |
Countries
China
Contacts
Public ContactXinhua Chen
Southern Medical University Southern Hospital
Outcome results
None listed