Effect of goal-directed fluid therapy based on the rate of change of carotid artery corrected flow time after passive leg raising on post-induction hypotension in gastrointestinal surgery

Effect of goal-directed fluid therapy based on the rate of change of carotid artery corrected flow time on post-induction hypotension in gastrointestinal surgery

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2600125563

Enrollment

Unknown

Registered

2026-05-28

Start date

2026-05-30

Completion date

Unknown

Last updated

2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

post-induction hypotension

Interventions

Observation group:None

target-directed fluid therapy group:Goal-directed fluid therapy guided by the rate of change of carotid corrected flow time

Conventional fluid therapy group:Conventional fluid therapy

Eligibility

Sex/Gender

All

Age

60 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. ASA physical status II or III 2. Age >= 60 years 3. Scheduled for elective gastrointestinal surgery under general intravenous anesthesia

Exclusion criteria

Exclusion criteria: 1. MAP > 120 mmHg before anesthesia induction 2. Previous history of any neck surgery or trauma 3. Severe liver dysfunction (Child-Pugh class > A) 4. Renal insufficiency (serum creatinine > 177 µmol/L) 5. Severe cardiovascular disease (NYHA > class 2, implanted pacemaker or cardioverter-defibrillator) 6. Patients taking oral angiotensin-converting enzyme inhibitors or oral angiotensin receptor blockers 7. Pregnant or lactating women 8. Surgery in the lateral or prone position 9. Poor ultrasound image quality 10. BMI > 30 kg/m² or < 15 kg/m²

Design outcomes

Primary

Measure	Time frame
Post-induction hypotension;	—

Secondary

Measure	Time frame
Carotid corrected flow time;Rate of change of carotid corrected flow time after passive leg raising;Lung Ultrasound Score;	—

Countries

China

Contacts

Public ContactKangli Hui

The General Hospital of Eastern Theater Command, People's Liberation Army of China

liuzhi9287@163.com+86 131 5123 5933

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Jun 11, 2026