Reconstruction of the Alveolar Process After Tooth Loss
Conditions
Interventions
Control group:No drilling procedure performed, autologous bone graft powder directly implanted into the bone augmentation area. 3D printed personalized titanium mesh used for space maintenance
Trial group 1:Three holes per tooth position uniformly created in the bone augmentation area, autologous bone graft powder implanted into the bone augmentation area. 3D printed personalized titanium m
Trial group 2:Six holes per tooth position uniformly created in the bone augmentation area, autologous bone graft powder implanted into the bone augmentation area. 3D printed personalized titanium mes
Sponsors
School and Hospital of Stomatology, Wenzhou Medical University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Aged over 18 years, either gender; 2. Severe atrophy of the alveolar process with bone volume insufficient for simultaneous implant placement, requiring bone augmentation surgery; 3. Willing to cooperate with imaging and histological examinations; 4. Stable systemic health status and able to tolerate implant surgery; 5. Good oral hygiene and able to cooperate with postoperative oral care and follow-up.
Exclusion criteria
Exclusion criteria: 1. Recent myocardial infarction (within 1 year); 2. Recent prosthetic valve surgery (within 1 year); 3. Severe renal insufficiency; 4. Uncontrolled endocrine disorders; 5. History of bisphosphonate or denosumab use; 6. Patients who have recently undergone radiotherapy or chemotherapy; 7. Drug or alcohol abuse; 8. Patients requiring regular steroid use; 9. Other conditions: psychiatric disorders, hematologic diseases (e.g., leukemia, hemophilia, coagulation disorders, etc.), cachexia, etc.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Percentage of new bone formation;Volume and density of regenerated bone; | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative complications; | — |
Countries
China
Contacts
Public ContactYang Ying
School and Hospital of Stomatology, Wenzhou Medical University
Outcome results
None listed