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Dynamic and Spatial Alterations of the Gut Microbiota During Colorectal Adenoma Progression and Its Non-Invasive Predictive Potential

Dynamic and Spatial Alterations of the Gut Microbiota During Colorectal Adenoma Progression and Its Non-Invasive Predictive Potential

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600125522
Enrollment
Unknown
Registered
2026-05-27
Start date
2026-06-01
Completion date
Unknown
Last updated
2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Colorectal adenoma

Interventions

Normal control group:None
Adenoma group:None

Sponsors

The First Hospital of Nanchang
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.Age >= 18 years old; 2.Undergoing colonoscopy for clinical indications; 3.No use of antibiotics, probiotics, or medications affecting the gut microbiota within 1 month prior to the procedure; 4.Voluntary participation in this study and signed informed consent.

Exclusion criteria

Exclusion criteria: 1.Previously diagnosed with colorectal cancer, inflammatory bowel disease, or hereditary colorectal cancer syndrome; 2.Acute intestinal infection within the past 1 month; 3.Presence of severe systemic diseases that, in the investigator’s opinion, make the subject unsuitable for enrollment; 4.Pregnant or breastfeeding women.

Design outcomes

Primary

MeasureTime frame
Core metrics in microbiome research: Alpha diversity, Beta diversity, and differential species screening indicators;In-depth evaluation recommendations;

Secondary

MeasureTime frame
Clinical-pathological correlation metrics;Diagnostic model performance metrics;

Countries

China

Contacts

Public ContactPeng Liu

The First Hospital of Nanchang

344840623@qq.com+86 791 8886 2387

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Jun 11, 2026