Acute Respiratory Distress Syndrome (ARDS)
Conditions
Interventions
Experimental Group:NIV-test Weaning Protocol
Control Group:SBT Weaning Protocol
Sponsors
Dazhou Central Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Inclusion Criteria for Medical Research? Age 18-80 years; 2. Acute respiratory distress syndrome (ARDS); 3. Expected invasive mechanical ventilation duration >= 24 hours; 4. First spontaneous breathing trial (SBT) failure.
Exclusion criteria
Exclusion criteria: 1. Any cause leading to disturbance of consciousness or increased intracranial pressure, neuromuscular disorders, severe cardiac dysfunction (New York Heart Association (NYHA) class III or IV, acute coronary syndrome (ACS), or persistent ventricular tachyarrhythmia), cardiogenic shock, or post-major cardiac surgery; 2. Severe hepatic or renal failure; 3. Severe malnutrition; 4. Injury to the upper airway or nasofacial region precluding the use of nasal (facial) masks; 5. Severe agitation expected to preclude cooperation with non-invasive ventilation (NIV).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 28-day ventilator-free days; | — |
Secondary
| Measure | Time frame |
|---|---|
| Duration of invasive mechanical ventilation;VAP incidence;Total duration of mechanical ventilation;Mortality rate; | — |
Countries
China
Contacts
Public ContactXiaoyi Liu
Dazhou Central Hospital
Outcome results
None listed