constipation
Conditions
Interventions
Spirulina group:Spirulina (1g per tablet, 1 tablet per dose, 3 times per day) induction period: 7 days
intervention period: 21 days
washout period: 14 days
take placebo (1g per tablet, 1 tablet per dose, 3 times per day) for 21 days.
Placebo group:Placebo (1g per tablet, 1 tablet per dose, 3 times a day) induction period: 7 days
washout period: 14 days. Take spirulina (1g per tablet, 1 tablet per dose, 3 times a day) for 21 days.
Sponsors
The Second Affiliated Hospital of Hainan Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Age >= 18 years old, gender not restricted; 2. Meet the diagnostic criteria for functional constipation; 3. Agree to participate in this study and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Previous diseases that cause weakness, cognitive impairment, aphasia, mental disorders or other conditions that may affect the patient's cooperation; 2. History of malignant tumors, severe cardiovascular or cerebrovascular diseases or history of abdominal surgery; 3. Patients with unexplained abdominal pain, patients with galactosemia and hyperuricemia; 4. Pregnant women, women preparing for pregnancy or breastfeeding women; 5. Patients who used antibiotics or probiotic preparations within 1 month before treatment or during treatment that may affect the intestinal flora; 6. Patients who did not take spirulina regularly, those who experienced adverse reactions or those considered unsuitable by the researchers.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The frequency of completely spontaneous defecation per week;Symptom Rating Scale for Constipation Patients Score;Hamilton Anxiety Scale score; | — |
Countries
China
Contacts
Public ContactFeihu Bai
The Second Affiliated Hospital of Hainan Medical University
Outcome results
None listed