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Effects of music synchronized exercise-cognitive training on cognitive and functional outcomes in patients with heart failure (MUSE-HF): a randomized controlled trial

Effects of music synchronized exercise-cognitive training on cognitive and functional outcomes in patients with heart failure (MUSE-HF): a randomized controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600125490
Enrollment
Unknown
Registered
2026-05-27
Start date
2026-05-29
Completion date
Unknown
Last updated
2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

heart failure

Interventions

Intervention group:Music synchronized exercise-cognitive training

Sponsors

The University of Hong Kong
Lead Sponsor

Eligibility

Sex/Gender
All
Age
60 Years to 90 Years

Inclusion criteria

Inclusion criteria: 1. are aged 60 years or older. 2. have a cardiologist-confirmed diagnosis of heart failure. 3. have NYHA Class II-III symptoms. 4. presence of mild cognitive impairment: 1) subjective memory complaints, and 2) objective cognitive decline, defined as a score of 18 to 25 on the Beijing version Montreal Cognitive Assessment (MoCA). 5. could walk without mobility aids. 6. can speak and comprehend Chinese.

Exclusion criteria

Exclusion criteria: 1. have a history of exercise-induced syncope or malignant ventricular arrhythmias. 2. confirmed diagnosis of dementia or delirium. 3. have neurological conditions that severely affect gait or mobility (e.g., Parkinson’s disease, multiple sclerosis, hemiparesis, and Huntington’s Disease). 4. are concurrently participating in or having completed structured cardiac rehabilitation within the past 6 months.

Design outcomes

Primary

MeasureTime frame
Global cognition;

Secondary

MeasureTime frame
Cognitive domains (attention, recall and working memory, processing speed, and executive function);Physical function;Slf-care;health-related quality of life;

Countries

China

Contacts

Public ContactQing Zhao

the University of Hong Kong

u3012089@connect.hku.hk+86 156 5158 0613

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Jun 11, 2026