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?PaO2/FiO2–mechanical energy dynamic subphenotypes and heterogeneous responses to individualized lung-protective tidal volume

?PaO2/FiO2–mechanical energy dynamic subphenotypes and heterogeneous responses to individualized lung-protective tidal volume

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600125458
Enrollment
Unknown
Registered
2026-05-27
Start date
2026-06-01
Completion date
Unknown
Last updated
2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sepsis

Interventions

Oxygenation mechanical energy antagonistic type:None
Oxygenation mechanical energy coordinated type:None

Sponsors

The First Affiliated Hospital of the Baotou Medical College of Inner Mongolia University of Science and Technology
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Age >= 18 years old; 2. Meet the criteria of Sepsis-3.0 and the Berlin definition for moderate to severe ARDS; 3. The daily tidal volume titration adjustment range is >= 1 mL/kg PBW; 4. Complete data.

Exclusion criteria

Exclusion criteria: 1. ECMO treatment; 2. Concurrent pneumothorax; 3. Missing key data > 20%; 4. Non-septic ARDS; 5. Cardiogenic pulmonary edema.

Design outcomes

Primary

MeasureTime frame
Oxygenation-related indicators;Respiratory mechanics indicators;28 days without a ventilator;7-day offline success rate;—

Countries

China

Contacts

Public ContactCui Qian

The First Affiliated Hospital of the Baotou Medical College of Inner Mongolia University of Science and Technology

cqdr0922@163.com+86 472 2178634

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Jun 11, 2026