Postoperative Pulmonary Complications
Conditions
Interventions
N group :In group N, intravenous infusion of norepinephrine (concentration: 8 µg/mL) was initiated immediately after general anesthesia induction at a starting dose of 0.01µg/kg/min. The infusion rate
E group :In group E, ephedrine at a concentration of 3 mg/mL was intravenously injected based on invasive arterial blood pressure after general anesthesia induction, with an initial dose of 3 mg. Repe
Sponsors
People's Hospital of Fuyang City
Eligibility
Sex/Gender
All
Age
65 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Patients aged 65 or above who are scheduled to undergo abdominal surgery and whose estimated operation duration is >= 2 hours; 2. American Society of Anesthesiologists (ASA) classification levels II-III; 3. Before the operation, the patient and their family members gave informed consent and signed the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Emergency surgery or surgery duration > 6 hours; 2. Preoperative presence of severe cardiac, hepatic or renal dysfunction; 3. Preoperative active pulmonary infection, severe chronic obstructive pulmonary disease or requiring home oxygen therapy; 4. Those who have received intravenous infusion of norepinephrine before the surgery; 5. Patients who are unable to sign the informed consent form for any reason; 6. Those who are known to be allergic to the drugs in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence of postoperative pulmonary complications (PPCs) during postoperative hospitalization;MMSE score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Length of hospital stay ;The incidence of AKI within 48 hours after surgery;Postoperative acute circulatory failure;The occurrence of surgical and medical complications within 30 days after surgery;Cardiac complications ;Length of ICU stay;Neurological complications ;Infectious complications; | — |
Countries
China
Contacts
Public ContactYang Fangfang
People's Hospital of Fuyang City
Outcome results
None listed