vernal keratoconjunctivitis
Conditions
Interventions
Severe VKC:None
Mild VKC:None
Moderate VKC:None
Health Group:None
Sponsors
Eye Hospital, Wenzhou Medical University
Eligibility
Sex/Gender
All
Age
8 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.Age = 8 years; 2.Children diagnosed with viral keratoconjunctivitis (VKC) in the active phase, or healthy children serving as controls; 3.Able to assist with meibomian gland function and ocular surface examinations; 4.The guardian must sign the informed consent form; children (aged 8 or older) must sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1.History of eye trauma or surgery; 2.Active eye infections other than vernal keratitis; 3.Use of topical or systemic medications that affect meibomian gland function within the past 3 months (e.g., azithromycin, doxycycline, isotretinoin, topical corticosteroids, immunosuppressants, antiallergic medications); 4.Confirmed infectious blepharitis; 5.Active, severe corneal ulcer that has not healed; 6.Wearing contact lenses (including soft, hard, and orthokeratology lenses); 7.Children with Bonini stage 4 (shield-shaped ulcer) or stage 5 (scarring stage);
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Area of the meibomian glands; | — |
Secondary
| Measure | Time frame |
|---|---|
| Conjunctival papillae;Degree of meibomian gland obstruction;Meibomian gland secretions;Erythema of the eyelid margin;FBUT;Conjunctival hyperemia;Corneal staining;Horner- Trantas;Conjunctival edema; | — |
Countries
China
Contacts
Public ContactWei Chen
Eye Hospital, Wenzhou Medical University
Outcome results
None listed