Effects of Comprehensive Exercise Training Combined with Repetitive Transcranial Magnetic Stimulation on Pain, Function, and Motor Cortex Reorganization in Patients with Chronic Neck Pain

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2600125427

Enrollment

Unknown

Registered

2026-05-26

Start date

2026-05-30

Completion date

Unknown

Last updated

2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cervical spondylosis

Interventions

control group:Implementing a comprehensive exercise training intervention

control group:Implementation of repetitive transcranial magnetic stimulation (rTMS)

Experimental group:Implementation of a Combined Exercise Training and Repetitive Transcranial Magnetic Stimulation Intervention

Eligibility

Sex/Gender

All

Age

18 Years to 45 Years

Inclusion criteria

Inclusion criteria: 1.Meets the diagnostic criteria for cervical spondylosis and has had neck pain for >=3 months; 2.Aged 18–45 years; 3. Visual Analog Scale (VAS) score of >=3; 4. Voluntarily participates in this study, is able to comply with the entire treatment plan, and signs an informed consent form.

Exclusion criteria

Exclusion criteria: 1.History of cervical spine surgery, fractures, tumors, infections, or inflammatory diseases; 2.Presence of neurological disorders (such as stroke or severe peripheral neuropathy) or severe psychological or psychiatric disorders; 3.Presence of TMS contraindications (such as intracranial metal implants or pacemakers); 4.Pregnant or breastfeeding women; 5.Patients with congenital musculoskeletal disorders, such as congenital torticollis or congenital myopathy; 6.Patients experiencing upper limb numbness, pain, or weakness caused by conditions outside the cervical spine (e.g., thoracic outlet syndrome, tennis elbow, carpal tunnel syndrome, cubital tunnel syndrome, frozen shoulder, long head of the biceps tendonitis, etc.); 7.Athletes or individuals who engage in regular fitness training; 8.Patients who have undergone acupuncture, massage, micro-needle knife therapy, or traction for shoulder or neck pain within the past month; 9.Patients with epilepsy or a family history of epilepsy; 10. Patients with neck pain accompanied by significant symptoms involving the nerve roots, vertebral arteries, or spinal cord; 11.Patients with severe cardiovascular or cerebrovascular diseases, or cognitive impairment.

Design outcomes

Primary

Measure	Time frame
Pain Assessment;Neck Functional Assessment;Assessment of Motor Cortex Reorganization;	—

Secondary

Measure	Time frame
Psychological Assessment;Quality of Life Assessment;	—

Countries

China

Contacts

Public ContactLou Zhenkui

Leshan People's Hospital, Sichuan Province

1573605095@qq.com+86 182 2759 7716

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Jun 11, 2026