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A Prospective, Multicenter Study Using Multiparameter Flow Cytometry to Detect Leukemia Stem Cells in Bone Marrow of Patients with Myeloproliferative Neoplasms for Predicting Leukemic Transformation and Prognosis

A Prospective, Multicenter Study Using Multiparameter Flow Cytometry to Detect Leukemia Stem Cells in Bone Marrow of Patients with Myeloproliferative Neoplasms for Predicting Leukemic Transformation and Prognosis

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600125419
Enrollment
Unknown
Registered
2026-05-26
Start date
2026-05-26
Completion date
Unknown
Last updated
2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Myeloproliferative Neoplasms

Interventions

myeloproliferative neoplasms:No specific intervention
treatment according to clinical guidelines.

Sponsors

The First Affiliated Hospital of Harbin Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Patients with newly diagnosed myeloproliferative neoplasms (MPN); 2. Aged 18 to 70 years; 3. All enrolled patients must provide written informed consent.

Exclusion criteria

Exclusion criteria: 1.Patients with chronic myeloid leukemia (CML); 2.Patients who are non-compliant or have poor compliance.

Design outcomes

Primary

MeasureTime frame
transformation into acute myeloid leukemia ;—

Secondary

MeasureTime frame
Overall survival;Progression free survival;Leukemia Transformation Time;—

Countries

China

Contacts

Public ContactShengjin Fan

The First Affiliated Hospital of Harbin Medical University

fansjhmu@163.com+86 133 0464 1978

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Jun 11, 2026