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Clinical Observation of the Incidence of Hypotension After General Anesthesia Induction with Equivalent Doses of Sufentanil and Alfentanil in Elderly Patients

Clinical Observation of the Incidence of Hypotension After General Anesthesia Induction with Equivalent Doses of Sufentanil and Alfentanil in Elderly Patients

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600125402
Enrollment
Unknown
Registered
2026-05-26
Start date
2025-12-01
Completion date
Unknown
Last updated
2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

post-induction hypotension

Interventions

Sufentanil induction group (Group S):None
Alfentanil induction group(Group A):None

Sponsors

Tianjin Medical University General Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
60 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Age >= 60years old; 2. ASA grade I - III, BMI 18 - 30kg/m²; 3. Scheduled to undergo elective non-cardiac surgery under general anesthesia; 4. Expected operation time > 1 hour.

Exclusion criteria

Exclusion criteria: 1. Severe cardiovascular disease; 2. Severe liver and kidney dysfunction; 3. Anticipated difficult airway; 4. Long-term use of opioid analgesics; 5. Allergy to the study drug or its components; 6. Refusal to sign the informed consent form.

Design outcomes

Primary

MeasureTime frame
Incidence of hypotension during general anaesthesia induction;—

Secondary

MeasureTime frame
Continuous invasive arterial monitoring;The incidence of severe hypotension;hypertension;bradyarrhythmia;tachycardia;The usage of vasoactive drugs;—

Countries

China

Contacts

Public ContactJia Zhen

Tianjin Medical University General Hospital

1464322162@qq.com+86 130 0221 1205

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Jun 11, 2026