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Exploring multimodal ultrasound imaging evaluation of microcirculation and cartilage elasticity of the femoral head in children

Exploring multimodal ultrasound imaging evaluation of microcirculation and cartilage elasticity of the femoral head in children

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600125397
Enrollment
Unknown
Registered
2026-05-26
Start date
2025-12-01
Completion date
Unknown
Last updated
2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Developmental dysplasia of the hip, suppurative hip arthritis, avascular necrosis of the femoral head,Perthes disease, transient synovitis,femoral fractures, femoral tumors

Interventions

Experimental group:None
Control group (elasticity imaging study only): Neonatal group:None
Control group (elasticity imaging study only): Infant group:None
Control group (elasticity imaging study only): Toddler group:None
Control group (elasticity imaging study only): Preschool-age group:None
Control group (elasticity imaging study only): School-age group:None
Control group (elasticity imaging study only): Adolescent group:None

Sponsors

Children's Hospital of Chongqing Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
No minimum to 18 Years

Inclusion criteria

Inclusion criteria: Experimental Group 1. Patients diagnosed with unilateral DDH, suppurative hip arthritis, avascular necrosis of the femoral head, femoral fractures, or other conditions necessitating hip surgery; 2. Age 0-18 years; 3. The patient or their family consent to undergo contrast-enhanced ultrasound and voluntarily participate in this project by signing the informed consent form; Control group inclusion criteria (elastography study only): Children undergoing health examinations at our hospital with no history of hip joint disease or surgery.

Exclusion criteria

Exclusion criteria: 1. Known hypersensitivity to sulfur hexafluoride (SF6) or any component of SonoVue®; 2. Have a clear history of rash or allergies in the past; 3. Children with conditions affecting cardiopulmonary function, including congenital heart disease with right-to-left shunt, severe pulmonary hypertension, critical respiratory failure, myocarditis, cardiomyopathy, pericarditis, endocarditis, arrhythmia, severe pneumonia, bronchial asthma, bleeding disorders, renal failure, and uncontrolled hypertension, as well as those requiring urgent surgical intervention; 4. Failure to obtain the consent of parents or legal guardians.

Design outcomes

Primary

MeasureTime frame
Vessel Density,VD;Flow Weighted Density of the vessel,FWVD;Perfusion Index,PI;Peak Intensity,PI;Ascending Slope,AS;viscosity coefficient;Shear wave velocity;Mean transit time,MTT;Fractal dimension,FD;Mean Velocity;Max Velocity;Time to peak;

Countries

China

Contacts

Public ContactTang Yi

Children's Hospital of Chongqing Medical University

tangyi6688@163.com+86 23 63630763

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Jun 11, 2026